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Emerging Cell‐based Therapies for SCI – A Review

Traumatic spinal cord injuries (SCIs) result in lifelong disability and financial burden for millions of patients and caregivers worldwide. Cell‐based therapies have emerged as a neuroprotective and neuroregenerative strategy for SCI, and now, a new STEM CELLS Translational Medicine article from the lab of Michael G. Fehlings (University of Toronto, Toronto, Ontario, Canada) highlights critical preclinical and clinical data in cell therapy with an emphasis on the pathobiology and mechanisms of recovery. Ahuja et al. also discusses adjunct treatments to maximize the efficacy of the grafts and important translational considerations such as clinical‐grade scale‐up and delivery techniques. This fascinating article succinctly provides readers with a working knowledge of SCI and cell therapies at the leading edge of research.