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Capillary-Resident EphA7-Positive Multipotent Pericytes

A current lack of markers for multipotent pericytes limits our understanding of their pathophysiological roles; however, researchers from the lab of Jun-ichi Kawabe (Asahikawa Medical University, Hokkaido, Japan) have now described how the implementation of EphA7 (Eph Receptor A7)  as a  marker to isolate pericytes from the microvessels of mouse subcutaneous adipose tissues. Yoshida et al. report in STEM CELLS Translational Medicine that these cells can form capillaries and display the ability to differentiate into mesenchymal and neuronal lineages, thereby suggesting their potential use in disease modeling and regenerative therapies.