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ASC Secretome Boosts hiPSC‐derived Cardiomyocyte Recovery

Heart transplantation is the primary option for patients with advanced heart failure; however, donor hearts are prone to rapid functional decline, limiting organ cold storage to 4 hours and preventing access of many patients to donor organs due to geographic distances. Recent research from the labs of Keith L. March (University of Florida, FL) and Pinar Zorlutuna (University of Notre Dame, IN, USA) sought to address the need to improve heart storage protocol and, in a new STEM CELLS article, Ellis et al. demonstrate that augmenting preservation solution with the adipose stem cell (ASC) secretome significantly improved both the degree of organ functional recovery and duration of acceptable organ storage.