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Press Releases from AlphaMed Press

September 28, 2021
Researchers report on new way to deliver healing stem cells to kidney injury patients

Durham, NC (September 28, 2021) – Scientists are reporting promising results in the early stages of a clinical trial designed to gauge the feasibility of a new type of treatment for people with acute kidney disease. Released in STEM CELLS Translational Medicine, the study shows how mesenchymal stromal cells (MSCs) delivered using a new ex vivo drug delivery system – SBI-101 – can keep MSCs viable longer and reprogram the peripheral immune response toward organ repair.

Acute kidney disease occurs when a kidney is suddenly unable to do its job of filtering blood and allows dangerous levels of waste to accumulate. The most severe cases require dialysis or a kidney transplant. Unfortunately, dialysis-dependent acute kidney injury has a mortality rate as high as 50 to 70 percent.

September 21, 2021
Repeated injury to airway stem cells could be major factor in chronic lung disease

Durham, NC ( September 21, 2021 ) – Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

The study determined that repeated injury to the epithelial tissue of the airways causes “biological aging” of the stem cells located there. “This premature aging of the tracheobronchial stem cells (TSCs) in turn may contribute to chronic lung disease,” explained Susan D. Reynolds, Ph.D., of Nationwide Children’s Hospital in Columbus, Ohio, and co-lead investigator of the new study along with Moumita Ghosh, Ph.D., University of Colorado School of Medicine, Anschutz Medical Campus.

September 16, 2021
Researchers explore promising new stem cell treatment for MRSA superbug

Durham, NC ( September 16, 2021 ) – A study released in STEM CELLS Translational Medicine (SCTM), by researchers at the Baker Institute for Animal Health, part of Cornell University’s College of Veterinary Medicine, Ithaca, N.Y., details in a relevant ex vivo model how treating wounds with the secretion of a type of stem cell called mesenchymal stromal cell (MSC) effectively reduced methicillin-resistant Staphylococcus aureus – better known as MRSA viability and stimulated the surrounding skin cells to build up a defense against the bacterial invader.

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August 24, 2021
Discovery that TRPV4 gene regulates cartilage growth might yield future therapies for joint repair

Durham, NC (August 24, 2021) – New information from a study reported on in STEM CELLS might result in more effective treatments for osteoarthritis and other cartilage diseases, as well as hereditary disorders affecting cartilage development. Their findings might also point to a new way to accelerate stem cell differentiation for bioengineering cartilage, the researchers say. 

August 18, 2021
Phase 1 clinical study reveals how stem cells alleviate COPD inflammation in humans

Durham, NC (August 18, 2021) – A new phase I clinical study shows, for the first time, how treatment with a type of stem cell called mesenchymal stromal cells is able to regulate important factors driving inflammation in patients with chronic obstructive pulmonary disease (COPD) for a period for time. The study, whose results were released in STEM CELLS Translational Medicine, provides insights that may aid in developing a new cellular therapy for treating COPD which is among the top five causes of morbidity and mortality worldwide – and other chronic airway diseases.

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August 16, 2021
Stem cell therapy restores injured tendons to full health in study on sheep

Durham, NC (August 16, 2021) – Tendon injuries in sheep that were treated with stem cell grafts achieved, in just two months, a diameter and hardness similar to the original healthy tendon, according to the results of a study released in STEM CELLS Translational Medicine (SCTM). These findings suggest that the treatment, which uses autologous adipose micrografts – grafts of stem cells derived from fat taken from the recipient – presents a safe, reliable and relatively fast way to promote tendon healing.

August 3, 2021
Study confirms safety of stem cell therapy for chronic knee pain

Durham, NC (August 3, 2021) – A study released in STEM CELLS Translational Medicine has confirmed the safety of a novel type of cellular therapy for knee pain caused by osteoarthritis. Conducted by a multi-institutional team of researchers in Japan who had developed the new therapy, the study was designed to confirm that their treatment – which involves transplanting the patient’s own mesenchymal stem cells (MSCs) into the affected knee – did not cause tumors.

July 27, 2021
Stem cell treatments alleviate muscular dystrophy symptoms in compassionate-use study

Durham, NC (July 27, 2021) - Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord. Led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, these WJ-MSC treatments resulted in significant improvement in several body muscles in most of the patients, with no serious side effects.

July 13, 2021
AlphaMed Press partners with Oxford University Press to publish journals

July 6, 2021 -  Oxford University Press (OUP) and AlphaMed Press are pleased to announce that OUP will publish three AlphaMed Press journals: The Oncologist, STEM CELLS, and STEM CELLS Translational Medicine beginning January 2022.

The Oncologist is a 26-year-old monthly, peer reviewed open access publication committed to helping cancer physicians excel in the constantly changing fields of oncology and hematology through the publication of timely reviews, original studies, and commentaries. The journal aims to help oncologists understand a range of disciplines by connecting translational research and clinical practice but also looks at the socioeconomic and psychosocial factors that determine access to care and quality of life and function following cancer treatment.

June 21, 2021
COVID-19 studies are bolstered by lung cells made from induced pluripotent stem cells

Durham, NC (June 21, 2021) - A team led by researchers at Newcastle University, UK has successfully created a model of the cells found in the lungs that can be used to replicate how COVID-19 infects the airways. This information, reported today in the STEM CELLS journal, paves the way for broader studies of viral lung infections using a cost-effective system that can easily be manufactured on a large scale.

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