The study, led by Dr. Fred Roisen of RhinoCyte™ Inc., has great implication for the estimated 5 million people worldwide affected by spinal cord injuries - 1.275 million of them in the United States alone, where the cost of treatment exceeds $40.5 billion each year.
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Coverage of the latest news and updates from the field of stem cells and regenerative medicine.
The move is part of Cytomedix's plan to expand from a wound-care based technology platform into a broader regenerative medicine company.
Until recently, SNHL was generally considered a permanent condition. But a new stem cell trial, which launched in January in the United States, could change that thinking.
CCTV reports that an industry analysis shows that at least 10,000 foreign patients come to China for stem cell treatments each year, and roughly 100 hospitals and clinics are offering the service.
It then alleges that Morales falsely represented to the public that he was a physician licensed to practice medicine in the United States and provided medical advice to individuals regarding the benefits of stem cell treatments.
The Kyoto team, led by Mitinori Saitou, used a three-step process. First they developed a very specific cocktail of three factors that were able to differentiate the stem cells into epiblast-like cells, a cell type that appears very transiently around Day 8 of embryo formation in mice.
When the researchers tracked the transplanted cells they found they migrated to a brain region known to support the growth of neurons, where the cells then developed into three types of neural tissue: neurons, astrocytes and oligodendrocytes.
To generate the iPSCs, the team followed the standard four-gene reprogramming procedure, but sought to minimize other potential sources of DNA mutations that might have influenced some previously reported results.
The findings were also published online in the Journal of the American Medical Association.
So far, however, nuclear transfer has not yet been successful in human cells. Many scientists have turned instead to stem cell lines created by reprogramming adult cells (usually skin cells) taken from patients.