Until recently, SNHL was generally considered a permanent condition. But a new stem cell trial, which launched in January in the United States, could change that thinking.
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Coverage of the latest news and updates from the field of stem cells and regenerative medicine.
CCTV reports that an industry analysis shows that at least 10,000 foreign patients come to China for stem cell treatments each year, and roughly 100 hospitals and clinics are offering the service.
It then alleges that Morales falsely represented to the public that he was a physician licensed to practice medicine in the United States and provided medical advice to individuals regarding the benefits of stem cell treatments.
The Kyoto team, led by Mitinori Saitou, used a three-step process. First they developed a very specific cocktail of three factors that were able to differentiate the stem cells into epiblast-like cells, a cell type that appears very transiently around Day 8 of embryo formation in mice.
When the researchers tracked the transplanted cells they found they migrated to a brain region known to support the growth of neurons, where the cells then developed into three types of neural tissue: neurons, astrocytes and oligodendrocytes.
To generate the iPSCs, the team followed the standard four-gene reprogramming procedure, but sought to minimize other potential sources of DNA mutations that might have influenced some previously reported results.
The findings were also published online in the Journal of the American Medical Association.
So far, however, nuclear transfer has not yet been successful in human cells. Many scientists have turned instead to stem cell lines created by reprogramming adult cells (usually skin cells) taken from patients.
Thirty-five patients received the cell transplant while 36 had sham surgery. After 12 months, the investigators found no significant difference in the motor scores of the two groups, with both improving approximately 21 percent.
Ten days later a second team of Stanford researchers, this time in the lab of Gerald Crabtree, published a Nature online report demonstrating how they had improved on Wernig's method and greatly increased the efficiency of converting skin to neuron.