A woman who suffered a severe heart attack in July was the first test subject, according to the research team at the Ottawa Hospital Research Institute (OHRI). Her heart had stopped beating before she was resuscitated, causing major damage to the cardiac muscle.
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Coverage of the latest news and updates from the field of stem cells and regenerative medicine.
Mark Stacy, M.D., vice dean for Clinical Research, Neurology at Duke University School of Medicine and an internationally recognized leader in the field of movement disorders including Parkinson's, will be the study's principal investigator.
Last year, researchers in the laboratory of Gladstone Institutes’ Cardiovascular and Stem Cell Research director Deepak Srivastava, MD, transformed scar-forming heart cells, part of a class of cells known as fibroblasts, into beating heart-muscle cells in live mice.
The researchers, all working within the university’s College of Medicine (UIC), investigated similarities between the transition of neural stem cells into neurons and the process whereby cancer cells invade surrounding tissues.
Now a new study in Japan is testing the safety and feasibility of using induced pluripotent stem cell (iPSC) taken from adult patients to treat their blindness.
Could harvesting stem cells for therapy one day be as simple as asking patients for a urine sample?
In adult mammals, neural stem cells proliferate in the brain's subventricular zone and hippocampal dentate gyrus, a part of the brain believed to play a critical role in memory development.
Cal-1 works to block CCR5, a protein that plays a critical role in enabling HIV to infect cells. Blocking it may provide the cells a protective shield against HIV, which in turn would help retain immune system functionality.
The finding offers the potential that these stem cells could somehow be turned back on, resulting in a new form of treatment for this aggressive disease.