In their study, published in the current issue of Cell Stem Cell, previously frozen stem cells restored production of sperm that successfully fertilized eggs to produce early embryos.
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Coverage of the latest news and updates from the field of stem cells.
The finding, reported in the Oct. 18, 2012, issue of Cell Reports, could lead to new treatments that speed recovery of healthy blood levels for patients receiving chemotherapy or undergoing bone marrow and cord blood transplants.
Relapse rates, non-relapse mortality and acute graft-versus-host disease (GHVD) also appear unaffected.
October 2012 — Nearly $20 million has been allocated to advance promising therapies in diabetes and Beta-thalassemia from the lab into clinical trials. The grants, from the California Institute for Regenerative Medicine (CIRM), were made this week to biotech companies ViaCyte Inc.
Embryonic stem cells go through a process called self-renewal in which they undergo multiple cycles of division while not differentiating into any other type of cells. This process is dependent on three protein networks, but how these networks are integrated posed a mystery.
DUCORD, derived from umbilical cord blood, has been approved for use in patients with disorders affecting the hematopoietic system — which produces the body’s blood cells —that are inherited, acquired or result from radiation treatment or chemotherapy.
Sir John B. Gurdon discovered that the specialization of cells is reversible when in a now-classic experiment conducted in 1962 he replaced the immature cell nucleus in a frog's egg cell with the nucleus of a mature intestinal cell. The modified cell developed into a normal tadpole.