Injury shifts the regenerating corticospinal motor neuron transcriptome towards an immature state, with the huntingtin gene acting as a central transcriptomic hub
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Article Scans
Brief reviews of recently published articles, organized by stem cell type.
July 6, 2020 | Mesenchymal Stem Cells
New research shows how MSC-secreted factors can impair biofilm formation by cutaneous wound‐related bacteria and disrupt mature biofilms via a protease‐dependent mechanism
July 6, 2020 | Mammalian Regeneration
Lin28-mediated conversion of inner-ear glia into neurons represents a new approach to the replacement of lost/damaged auditory nerves and the reversal of hearing loss
July 6, 2020 | Mammalian Regeneration
New research finds that overexpression of Myc and a transcription elongation factor promotes cardiomyocyte proliferation in the adult mouse heart
June 15, 2020 | ESCs/iPSCs
An improved protocol for the generation of ventral midbrain neurons from human iPSCs may promote the development of novel cell-therapies for Parkinson’s disease patients
June 15, 2020 | Cardiac Stem Cells
New research highlights the zinc-finger of the cerebellum 2 (ZIC2) gene as an essential factor in the formation of human cardiac progenitor cells from embryonic stem cells
June 15, 2020 | ESCs/iPSCs
The chemical reversion of human iPSCs to a naïve state permits the differentiation of vascular progenitor cells with an improved ability to treat diabetes-related conditions
June 8, 2020 | ESCs/iPSCs
Endothelial cells differentiated from patient-specific induced pluripotent stem cells can function as clotting factor delivery vehicles for the treatment of hemophilia A
June 8, 2020 | Adipose Stem Cells
Research highlights endothelial growth medium for adipose-derived stem cell maintenance, expansion, and beige adipocyte differentiation and describes the crucial role of TGFβ1
June 8, 2020 | ESCs/iPSCs
Researchers explore embryo complementation with human induced pluripotent stem cells to rescue ETV2-mutant embryos and generate donor-cell derived hematoendothelium
