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Article Scans

Brief reviews of recently published articles, organized by stem cell type.

May 11, 2020 | Neural Stem Cells

A new study explores the complex responses of neural stem cells to elevated levels of damaged proteins to highlight mechanisms that could enhance adult neurogenesis

May 4, 2020 | ESCs/iPSCs

A study implicates in vitro expansion as a primary determining factor in cardiac interstitial cell adaptability and highlight a role for the host tissue microenvironment

May 4, 2020 | ESCs/iPSCs

Researchers demonstrate that nicotinamide adenine dinucleotide supports the pluripotent state of human embryonic stem cells through the regulation of metabolism

May 4, 2020 | ESCs/iPSCs

Research suggests that the actin cytoskeleton can significantly impact the differentiation of human pluripotent stem cells into functional pancreatic β cells

April 27, 2020 | Mesenchymal Stem Cells

A new study suggests that GARP-mediated regulation of TGF‐β activation/signaling can allow mesenchymal stem cells to safely proliferate under stress-inducing conditions

April 27, 2020 | Neural Stem Cells

Researchers establish that the miR‐137 microRNA modulates human neural stem cell fate by influencing mitochondrial dynamics through a number of mechanisms

April 27, 2020 | Technology

Inhibiting fatty-acid utilization can reduce the reactive oxygen species-mediated DNA damage response and promote cardiomyocyte proliferation in the postnatal mouse heart

April 20, 2020 | Adipose Stem Cells

Fibroblast growth factor 2 promotes the initial expansion of ASCs through a STAT3‐dependent response, although continuous exposure limits their long‐term proliferation

April 20, 2020 | ESCs/iPSCs

Researchers demonstrate that tissue inhibitor of metalloproteinase proteins may inhibit PSC‐derived teratoma formation through cell cycle arrest and increased apoptosis

April 20, 2020 | Technology

A comparison of the transcriptomes of the developing human cortex and cortical organoids at the single-cell level provide evidence for stress-mediated differences