Lowering the intracellular pH can induce the maturation of endothelial cells derived from human induced pluripotent stem cells and hence enhance their regenerative potential
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Brief reviews of recently published articles, organized by stem cell type.
The RhoA-YAP-β‐catenin signaling axis senses and transduces mechanical cues from the extracellular matrix to promote the expansion of inner ear progenitor cells...
A small molecule cocktail can induce the transformation of fibroblasts into rod photoreceptor-like cells with the potential to restore vision loss
New research explores the modulation of the immune system following the transplantation of muscle stem cells into a mouse model of inflammatory bowel disease
Bone marrow stromal cells express CXCR4 and bone marrow SDF‐1‐CXCR4 signaling regulates HSPC maintenance, self‐renewal, and hematopoietic reconstitution
Injury shifts the regenerating corticospinal motor neuron transcriptome towards an immature state, with the huntingtin gene acting as a central transcriptomic hub
New research shows how MSC-secreted factors can impair biofilm formation by cutaneous wound‐related bacteria and disrupt mature biofilms via a protease‐dependent mechanism
Lin28-mediated conversion of inner-ear glia into neurons represents a new approach to the replacement of lost/damaged auditory nerves and the reversal of hearing loss
New research finds that overexpression of Myc and a transcription elongation factor promotes cardiomyocyte proliferation in the adult mouse heart
An improved protocol for the generation of ventral midbrain neurons from human iPSCs may promote the development of novel cell-therapies for Parkinson’s disease patients