While transplanted human iPSC-derived skeletal muscle cells become infiltrated by immune cells after transplantation, this does not negatively impact engraftment
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Brief reviews of recently published articles, organized by stem cell type.
The ASC secretome may lengthen heart storage time before significant deterioration, thereby increasing the number of available hearts for transplantation
A study reports a microfluidic “heart-on-a-chip” system and its validation via an analysis of responses...
Amniotic fluid stem cell-derived exosomal microRNAs activate pro‐survival and anti‐apoptotic pathways in a cell-based ischemia/reperfusion-injury model system
A new study confirms that alveolar type I cells present in induced pluripotent stem cell‐derived alveolar organoids closely resemble primary alveolar cells
HIV studies boosted by the development of a CCR5-edited Mauritian cynomolgus macaque model via gene-editing of embryos
Advanced in vitro drug screening platform may significantly accelerate the identification of novel drugs for the treatment of atrial fibrillation
A new study provides evidence for the utility of DHODH inhibitors such as brequinar in the development of safe and effective PSC‐based therapies
Cellular physical properties can promote intestinal stem cell self-renewal by inducing intracellular crowding and maintaining an elevated response to Wnt ligands
Research using iPSC-derived organoids support primary cell‐intrinsic and secondary mechanical causes of altered development in the congenital diaphragmatic hernia lung