Wide-raging analyses support the safety of human embryonic stem cell‐derived retinal pigment epithelium generated by an optimized in vitro differentiation methodology
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Brief reviews of recently published articles, organized by stem cell type.
The H19 lncRNA mediates stroke‐augmented neurogenesis in neural stem cells through a mechanism involving chromatin remodeling proteins
A phase II clinical trial evaluates the efficacy of CD34-positive EPC treatment in improving renal function and clinical outcomes in chronic kidney disease patients
Homogenous populations of perivascular-like MSCs might exhibit more robust responses to inflammatory insult and provide a more “powerful” therapeutic approach
Lowering the intracellular pH can induce the maturation of endothelial cells derived from human induced pluripotent stem cells and hence enhance their regenerative potential
The RhoA-YAP-β‐catenin signaling axis senses and transduces mechanical cues from the extracellular matrix to promote the expansion of inner ear progenitor cells...
A small molecule cocktail can induce the transformation of fibroblasts into rod photoreceptor-like cells with the potential to restore vision loss
New research explores the modulation of the immune system following the transplantation of muscle stem cells into a mouse model of inflammatory bowel disease
Bone marrow stromal cells express CXCR4 and bone marrow SDF‐1‐CXCR4 signaling regulates HSPC maintenance, self‐renewal, and hematopoietic reconstitution
Injury shifts the regenerating corticospinal motor neuron transcriptome towards an immature state, with the huntingtin gene acting as a central transcriptomic hub