Body: Scientists have discovered a combination of two commonly available drugs that could help the body heal spinal fractures.
Body: Scientists show for the first time that a newer type of CRISPR, called base-editing, can safely cure cystic fibrosis in stem cells derived from patients.
Body: Scientists find that normal intestinal cells 'de-differentiate' en masse into stem cells that generate the cells needed for a healthy intestinal lining. New study establishes de-differentiation as the predominant mode of stem cell recover in the intestine.
Body: Researchers have revealed how an essential protein helps to activate genomic DNA during the conversion of regular adult human cells into stem cells.
Body: New research has deciphered how rogue communications in blood stem cells can cause leukemia. The discovery could pave the way for new, targeted medical treatments that block this process.
Body: Nw study findings implicate a specific type of immune cell behind heterotopic ossification, or abnormal bone formation and present a possible target for treatment.
Body: Recently, a type of biodegradable hydrogel, dubbed microporous annealed particle (MAP) hydrogel, has gained much attention for its potential to deliver stem cells for body tissue repair. But it is currently unclear how these jelly-like materials affect the growth of their precious cellular cargo, thereby limiting its use in regenerative medicine.
Body: Scientists have developed a new TREE method (an acronym short for transient reporter for editing enrichment, or TREE), which allows for bulk enrichment of DNA base-edited cell populations -- and for the first time, high efficiency in human stem cell lines.
Body: Scientists used molecular motors to manipulate the protein matrix on which bone marrow-derived mesenchymal stem cells are grown. Rotating motors altered the protein structure, which resulted in a bias of the stem cells to differentiate into bone cells (osteoblasts). Without rotation, the stem cells tended to remain multipotent.
Body: Researchers describe a new method for delivering neural precursor cells to spinal cord injuries in rats, reducing the risk of further injury and boosting the propagation of potentially reparative cells.