Body: One of the largest problems with cancer treatment is the development of resistance to anticancer therapies. A research team found that repurposing a commonly used chemotherapy drug using a nanoparticle was more effective than both a solution of the pure drug and other available treatments.
Body: Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting. Researchers have now created superior bone grafts using primitive stem cells. They found that these cells help create very fertile scaffolds needed for bone to regenerate at the site of repair.
Body: Researchers have found two genes that regulate the differentiation of stem cells in the small intestine, offering valuable insight into how the body develops and maintains a healthy gut.
Body: Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers have created natural killer cells -- a type of immune cell -- with measurably stronger activity against a form of leukemia, both in vivo and in vitro.
Body: A new study shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication and that fish oil, when tested in the model, created an antidepressant response.
Body: More than 3 million Americans have glaucoma, a serious eye condition causing vision loss. Using human stem cell models, researchers found they could analyze deficits within cells damaged by glaucoma, with the potential to use this information to develop new strategies to slow the disease process.
Body: An experimental cancer drug can extend the life of mice with Rett Syndrome, a devastating genetic disorder that afflicts about one of every 10,000 to 15,000 girls within 6 to 18 months after birth.
Body: Study based on a decade of research and treatment shows no difference in overall survival between cord blood and matched related donor as source for stem cell transplant, with reduced graft-versus-host disease in patients using cord blood.
Body: Some plastic surgeons have been using stem cells to treat aging, sun-damaged skin. But while they've been getting good results, it's been unclear exactly how these treatments work to rejuvenate 'photoaged' facial skin. A new study finds that within a few weeks, stem cell treatment eliminates the sun-damaged elastin network and replacing them with normal, undamaged tissues and structures.
Body: Stem cell researchers have designed a model of an early embryonic brain. The model will increase our understanding of how the human brain develops and can thereby help to accelerate the development of stem cell treatments for brain disorders such as Parkinson's disease, epilepsy and dementia.