Body: Researchers have shown by in vitro experimentation that changes of glycans in mouse epidermal stem cells may serve as a biomarker of aging. Further, by overexpression of specific glycogenes in mouse keratinocytes, they replicated the glycome profile of aging cells as well as their decreased proliferation ability. These findings hold promise for stem cell research into skin disorders, specifically senile degeneration, wound healing and skin cancer.
Body: Researchers have discovered that the cells that cause goosebumps are also important for regulating the stem cells that regenerate hair. In the skin, the muscle that contracts to create goosebumps is necessary to bridge the sympathetic nerve's connection to hair follicle stem cells. The sympathetic nerve reacts to cold by contracting the muscle and causing goosebumps in the short term, and by driving stem cell activation and new hair growth over the long term.
Body: In a groundbreaking new study, researchers have 3D printed a functioning centimeter-scale human heart pump in the lab. The discovery could have major implications for studying heart disease, the leading cause of death in the United States killing more than 600,000 people a year.
Body: In one of the first studies addressing the role of sex hormones' impact on stem cells in the gut, scientists outline new insights showing how a steroidal sex hormone, ecdysone, drastically alters the way intestinal stem cells behave, ultimately affecting the overarching structure and function of this critical organ.
Body: If every cell has the same genetic blueprint, why does an eye cell look and act so differently than a brain cell or skin cell? In a new study, researchers come one step closer to solving this mystery, showing RNA plays a critical role.
Body: Without stem cells, human life would not exist. Due to them, a lump of cells becomes an organ, and a fertilized egg develops into a baby. But what actually makes a stem cell? Are these a stable population of specially gifted cells? Scientists discovered that instead, stem cells might emerge due to the collective behavior of cells within the organs.
Body: Cell reprogramming provides an outstanding opportunity for the artificial generation of stem cells for regenerative medicine approaches in the clinic. As current cell reprogramming methods are low in efficiency, researchers around the globe aim to learn lessons from the early embryo which might lead them to a more efficient and faster generation of high-quality, fully reprogrammed stem cells.
Body: A new approach could illuminate a critical stage in the life cycle of one of the most common malaria parasites.
Body: Scientists are whispering the secrets of a simpler way to generate the sensory cells of the inner ear. Their approach uses direct reprogramming to produce sensory cells known as 'hair cells,' due to their hair-like protrusions that sense sound waves.
Body: A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.