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October 16, 2020
Body: Biologists reveal that tissue perturbations by chemotherapy agents promote stem cell expansion and that fibroblast cells exhibit unexpected, immune-like behavior.
October 13, 2020
Body: To make organoids grow faster, give them a squeeze, suggests a new study, which finds compressing cells, and crowding their contents, can coax them to grow and divide. The results may lead to faster way to grow artificial organs.
October 13, 2020
Body: Medical researchers have identified a mechanism that is likely to prevent hair loss.
October 12, 2020
Body: Researchers have generated mice lacking the estrogen receptor beta gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice. This was not observed in male mice that lacked the ER-beta gene, suggesting that estrogen and its downstream signals may be a female-specific mechanism for muscle growth and regeneration.
October 12, 2020
Body: Researchers building a model of muscle damage in a cultured system found that components leaking from broken muscle fibers activate ''satellite cells,'' which are muscle stem cells. While attempting to identify the activating proteins, they found that metabolic enzymes, such as GAPDH, rapidly activated quiescent satellite cells and accelerated muscle injury regeneration. This is a highly rational and efficient regeneration mechanism, in which the damaged muscle itself activates satellite cells for regeneration.
October 8, 2020
Body: A team has developed a thermoresponsive nanotopography cell culture platform.
October 5, 2020
Body: Minor changes in immune cells can significantly affect the immune response, scientists have now discovered. Their findings could be relevant for stem cell therapy.
October 2, 2020
Body: Scientists have discovered that a specific type of molecule may stimulate stem cells to regenerate, reversing the inflammation caused by periodontal disease.
October 1, 2020
Body: In September 2015, the US National Institutes of Health placed a funding moratorium on research that involves introducing human pluripotent stem cells into animal embryos. To assess attitudes on human-animal chimeric embryo research, investigators conducted a survey among 430 Americans. The results of the survey found that 82% of people are supportive of at least some parts of this research.
October 1, 2020
Body: Researchers investigated the effects of adipose-derived stem cells (ADSCs) loaded with the antibiotic ciprofloxacin on osteomyelitis caused by implants. By administering ADSC-loaded ciprofloxacin to the site of bone infection in rats, the researchers found a significant improvement of the infection, as shown by reduced soft tissue swelling, abscess formation, and bone degradation. These findings suggest a potential new therapy for implant-related bone infections that have traditionally been difficult to treat with antibiotics.