Body: Investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring. Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer's recurrence.
Body: Scientists have now been able to unravel a mystery surrounding the question of how cells use their sense of touch to make vital decisions during embryogenesis.
Body: In people with active secondary progressive multiple sclerosis (MS), hematopoietic stem cell transplants may delay disability longer than some other MS medications, according to a new study. The study involved autologous hematopoietic stem cell transplants, which use healthy blood stem cells from a person's own body to replace diseased cells.
Body: Senescent cells, which emerge after tissue injury, create an aged-like inflamed microenvironment that is negative for stem cell function and tissue repair. The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people and for improving muscle repair in young healthy people.
Body: Experts are investigating how cells called Muller glial cells, responsible for regenerating a damaged zebrafish retina, acquire stem cell properties with the hope of eventually developing techniques to encourage human retinas to regenerate.
Body: Researchers have shown that the retinoid and unsaturated fatty acid sensor RXR is a key protein in the maintenance of a balanced production of the different types of blood cells.
Body: An ancient fish called a 'living fossil' has helped researchers understand the basics of stem cells. This will further stem cell research and be a step in the direction of creating artificial organs.
Body: During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens. Scientists have now found an epigenetic switch in blood stem cells and progenitor cells of mice that can trigger the switch from one mode to the other.
Body: Researchers have identified the cellular mechanism and molecular trajectory for the formation of adult pluripotent stem cells in the acoel worm, Hofstenia miamia.
Body: Cartilage degeneration and injuries affect 350 million people worldwide. Patients with these conditions experience increased pain and discomfort over time. However, an exciting breakthrough in tissue regeneration research offers the promise of meaningful relief.