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May 10, 2024
Body: Researchers have identified molecular and genetic pathways that direct the generation and maturation of parietal cells, the only cells in the body that produce acid, from stem cells. The findings can lead to new strategies to regulate parietal cell function in different diseases involving these cells, including autoimmune gastritis and stomach and esophageal cancers.
May 10, 2024
Body: Scientists reveal how ETV4 controls stem cell differentiation in response to mechanical cues.
May 9, 2024
Body: Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth. The precision of these aging clocks suggests that the aging process follows a program. Scientists have now discovered that aging clocks actually measure the increase in stochastic changes in cells.
April 30, 2024
Body: Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for understanding kidney development, modeling diseases, and discovering new treatments. The team improved the chemical cocktail for generating and growing NPCs in the laboratory, enabling the sustained growth of both mouse and human NPCs in a simple 2-dimensional format.
April 30, 2024
Body: Researchers have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective treatments.
April 22, 2024
Body: Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study.
April 11, 2024
Body: Neural crest cells -- embryonic pluripotent cells within the facial primordium -- may be necessary for forming proper animal facial structures. Researchers have produced neural crest cell-rich aggregates from human pluripotent stem cells and developed a method to differentiate them in cell populations with a branchial arch-like gene expression pattern.
April 10, 2024
Body: University of Montana researchers and their partners have found a new method to generate human cartilage of the head and neck.
April 4, 2024
Body: Researchers have succeeded in correcting a gene defect that causes a hereditary liver disease and its adverse effects on cells.
April 4, 2024
Body: A traumatic brain injury (TBI) can quadruple your risk for developing dementia and increase your chances of developing neurodegenerative diseases such as ALS. In a new study scientists use lab-grown human brain structures known as organoids to offer insights into why this is the case and how to mitigate the risk.