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October 19, 2021
Body: A new study shows that functional sperm cells can be made in a dish using primate embryonic stem cells.
October 18, 2021
Body: A recent study examining the therapeutic potential of photoreceptor precursors, derived from clinically compliant induced pluripotent stem cells (iPSC), has demonstrated the safety and therapeutic potential of clinically compliant iPSC-derived photoreceptor precursors as a cell replacement source for future clinical trials.
October 15, 2021
Body: Researchers have found that the ability of skin stem cells to heal wounds is linked with their ability to move towards the injury. Their study identified the signalling pathway of EGFR and COL17A1 as a key player in the regulation of motility. Understanding mechanisms that underlie the age-associated reduction in regenerative capacity is the first step to develop targeted treatments for age-associated chronic nonhealing disorders, such as diabetic ulcers.
October 14, 2021
Body: Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, the replacement structure is an imperfect cartilage tube. Now, a study describes how stem cells can help lizards regenerate better tails.
October 13, 2021
Body: More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system. Very often, the so-called graft-versus-host reaction occurs, an inflammatory disease that can affect different organs and is caused by an unwanted defense reaction of the donor cells and the body's own T cells. Scientists now show how these endogenous, tissue-derived T cells enter other organs, such as the intestine, via the blood and contribute to inflammation there. The study provides important approaches to better therapy in stem cell transplantation and new diagnostic options.
October 8, 2021
Body: Our DNA is very similar to that of the chimpanzee, which in evolutionary terms is our closest living relative. Stem cell researchers have now found a previously overlooked part of our DNA, so-called non-coded DNA, that appears to contribute to a difference which, despite all our similarities, may explain why our brains work differently.
October 2, 2021
Body: Vision loss can be a side effect from stroke. Neurons don't regenerate, and stem cell therapy is costly, difficult, and chancy. Researchers have figured out a way to use gene therapy to recover lost vision after a stroke in a mouse model.
September 29, 2021
Body: Stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration.
September 28, 2021
Body: Dry eye disease (DED) affects up to 50% of the U.S. population, costing the nation's health care system approximately $50 billion annually. A team recently completed a clinical trial using corneal epithelial stem cells to improve outcomes for DED patients.
September 28, 2021
Body: Researchers have invented a new way to generate human cartilage tissue from stem cells. The technique could pave the way for the development of a much-needed new treatment for people with cartilage damage.