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iPSC-Reprogramming Keeps it Nice and Splice-y!

New research highlights the importance of alternative splicing at various stages of iPSC reprogramming

Correlation of Age and Mitochondrial Mutations in iPSCs

Research suggests that iPSCs generated from older patient samples are more likely to carry higher levels of mitochondrial DNA damage which could affect their therapeutic application

Microchamber, Mega mESC Pluripotency!

Researchers successfully apply a microchamber culture strategy for mESCs which potentiates endogenous signaling to promote pluripotency

Tackling Loss of Hearing with Mutation Correction of Patient Specific Stem Cells

Using patient specific induced pluripotent stem cells, a new study shows that cell-based treatments for deafness may be a future possibility

Mimicking Ocular Development and Treating Corneal Blindness using iPSCs

Researchers describe how multilayered ocular structures generated from iPSCs may provide a patient-specific means to treat forms of blindness

Boosting Vascular Therapies by Modulating the Microenvironment?

A Stem Cells study shows that modulating a microenvironmental factor can alter smooth muscle cell differentiation from ESCs; knowledge which could boost vascular therapies.

A Safe and Effective Means to Produce and Transplant iPSC-Derived Progenitors?

New research in SCTM describes a safe and effective new strategy for the treatment of type 1 diabetes using induced pluripotent stem cell-derived progenitors

Retinal Differentiation of mRNA-Reprogrammed iPSCs – Safe and Efficient!

A new study describes the successful retinal differentiation of induced pluripotent stem cells generated using mRNA, a strategy which may be more clinically relevant than traditional strategies

Cardiac Differentiation of ESCs - A New Role for REST

New research describes a novel role for the REST transcription factor in the cardiac-specific differentiation of embryonic stem cells

First Description of Pluripotent Stem Cell-derived Functional Sperm

Researchers describe the first evidence of the production of functional sperm-like cells from mouse embryonic stem cells

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