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Preclinical Assessment for hESC-derived Oligodendrocyte Progenitor Cells for Cervical Spinal Cord Injury

An exciting new animal study suggests that oligodendrocyte progenitor cells derived from human ESCs are safe for the treatment of cervical spinal cord injury

Comparative Study Highlights Utility of iPSC-derived Cardiomyocytes

A cardiomyocyte showdown suggests that cells derived from different PSC sources demonstrate similar characteristics and functionality following transplantation

TEC-mediated FGF2 Secretion Controls hPSC Pluripotency

A new study describes the discovery of a novel regulator of basic fibroblast growth factor 2-mediated pluripotency

Stem Cell Therapy for Parkinson's Disease - Which Cell is Best?

A comparative study indicates that immature dopaminergic neurons derived from hPSCs represent the ideal cell type for replacement therapy in Parkinson’s Disease

 

Organoid Analysis Highlights the Intercellular Signaling Processes controlling Hepatogenesis

A single-cell RNA sequencing study of liver organoids provides insight into the signaling processes that control three-dimensional organ development 

iPSC-derived Vascular Cells Go with the Flow!

A new study shows that exposure to blood flow hemodynamics can improve the maturation of vascular cells derived from induced pluripotent stem cells

iPSCs and CRISPR/Cas9 Combine to Faithfully Model CoQ10 Deficiency

Two exciting technologies collide to facilitate the modeling of a rare genetic disease and provide a means to discover new treatment strategies

Saving an Endangered Species: iPSC Technology to the Rescue?!

Studies into sex determination using induced pluripotent stem cells leads to a potential strategy to conserve an endangered species

From Exploring CGI Protection to Epigenomic Editing in Pluripotent Stem Cells

A study exploring DNA methylation processes has uncovered an exciting new means to edit the epigenome in pluripotent stem cells

The Safe, Effective, and Non-Invasive Production of Induced Pluripotent Stem Cells from Down Syndrome Patients

A new means to generate Down Syndrome specific iPSCs may lead to enhanced cell-based treatments for associated pathologies and a deeper understanding of disease development

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