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Organoid Analysis Highlights the Intercellular Signaling Processes controlling Hepatogenesis

A single-cell RNA sequencing study of liver organoids provides insight into the signaling processes that control three-dimensional organ development 

iPSC-derived Vascular Cells Go with the Flow!

A new study shows that exposure to blood flow hemodynamics can improve the maturation of vascular cells derived from induced pluripotent stem cells

iPSCs and CRISPR/Cas9 Combine to Faithfully Model CoQ10 Deficiency

Two exciting technologies collide to facilitate the modeling of a rare genetic disease and provide a means to discover new treatment strategies

Saving an Endangered Species: iPSC Technology to the Rescue?!

Studies into sex determination using induced pluripotent stem cells leads to a potential strategy to conserve an endangered species

From Exploring CGI Protection to Epigenomic Editing in Pluripotent Stem Cells

A study exploring DNA methylation processes has uncovered an exciting new means to edit the epigenome in pluripotent stem cells

The Safe, Effective, and Non-Invasive Production of Induced Pluripotent Stem Cells from Down Syndrome Patients

A new means to generate Down Syndrome specific iPSCs may lead to enhanced cell-based treatments for associated pathologies and a deeper understanding of disease development

Chemical Cocktail Creates Extended Pluripotent Stem Cells

Researchers describe a new chemical cocktail that enables pluripotent stem cells to form embryonic and extraembryonic tissues

Long-term Neuronal Cell Transplant Study Highlights Long-Distance Neural Growth

A new study finds that progressive electrophysiological and morphological maturation of transplanted iPSC-derived neural cells occurs over long-time periods in vivo

Innate Immune Pathway Stimulation Enhances Reprogramming Strategies

A new study learns that the activation of the innate immune system enhances the reprogramming of somatic cells into other fates

Will an Enhanced Endothelial Cell Differentiation Strategy Leave CVDs “Quaking” in their Boots?

The overexpression of an RNA binding protein enhances endothelial cell differentiation from induced pluripotent stem cells and may improve the treatment of cardiovascular disease patients

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