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Haematopoetic Stem Cells

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Unexpected Findings Reveal a Complex Role for the NF-κB pathway in Hematopoiesis

Studies into the role of the non-canonical NF-κB signaling pathway provide unexpected findings and new insight into the regulation of the hematopoiesis and bone marrow failure

Differentiating HSCs from Pluripotent Stem Cells: The Disrupting Role of ROS

A new study demonstrates how reactive oxygen species can disrupt the differentiation of hematopoietic stem cells from pluripotent stem cells

Induced Erythroid Progenitors – A New Means to Produce Mature RBCs?

New research suggests that the production of induced erythroid progenitors could, in the future, be an effective means to produce red blood cells for transplantation purposes

Liver Regeneration using Blood-derived Hepatocytes

Using a simple conversion technique, researchers have generated hepatocytes from blood progenitors and have demonstrated their liver regeneration capacity in vivo

Reselected Hematopoietic Progenitors as a Treatment for Diabetes?

A new Stem Cells study shows that reselected progenitor cells from cord blood may be an effective treatment for pancreatic β cell loss

Removing Senescent Cells Gives Back HSCs their Youth

Researchers discover a means to selectively ablate senescent cells and, in doing so, find that this can rejuvenate stem cell populations

Getting Physical (and Chemical) to Enhance Platelet Production

Researchers boost platelet production from cord blood hematopoietic stem/progenitor cells using a defined 3D culture system

Overturning the Classical View of the Hematopoietic System

A new study shakes the hematopoietic foundations and reveals a new view of how blood is formed in mice.

Normal and Leukemic Stem Cells Fight for a Place to Call Home

A new study demonstrates that normal and leukemic blood stem cells fight for the same niche with consequences for cancer treatment and transplantation.

A New Route for Stem Cell-based Cardiac Disease Therapy

The results of a new trial demonstrate an improved method to deliver stem cells to the failing heart.

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