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Haematopoetic Stem Cells

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New Model System Describes the Importance of Smarca5 to Hematopoiesis

Researchers investigate the role of the Smarca5 chromatin remodelling factor in hematopoiesis using a new conditional knockout animal model

It's What's on the Inside That Counts for Newly Identified Human Blood Cells!

RNA-based analysis suggests the existence of additional blood immune cells not identified by the expression of surface markers or morphology

Breathing and Making Blood? – A new Role for the Lungs

A new study now indicates that the lungs contain hematopoietic progenitors and contribute significantly to platelet formation 

 

Unexpected Findings Reveal a Complex Role for the NF-κB pathway in Hematopoiesis

Studies into the role of the non-canonical NF-κB signaling pathway provide unexpected findings and new insight into the regulation of the hematopoiesis and bone marrow failure

Differentiating HSCs from Pluripotent Stem Cells: The Disrupting Role of ROS

A new study demonstrates how reactive oxygen species can disrupt the differentiation of hematopoietic stem cells from pluripotent stem cells

Induced Erythroid Progenitors – A New Means to Produce Mature RBCs?

New research suggests that the production of induced erythroid progenitors could, in the future, be an effective means to produce red blood cells for transplantation purposes

Liver Regeneration using Blood-derived Hepatocytes

Using a simple conversion technique, researchers have generated hepatocytes from blood progenitors and have demonstrated their liver regeneration capacity in vivo

Reselected Hematopoietic Progenitors as a Treatment for Diabetes?

A new Stem Cells study shows that reselected progenitor cells from cord blood may be an effective treatment for pancreatic β cell loss

Removing Senescent Cells Gives Back HSCs their Youth

Researchers discover a means to selectively ablate senescent cells and, in doing so, find that this can rejuvenate stem cell populations

Getting Physical (and Chemical) to Enhance Platelet Production

Researchers boost platelet production from cord blood hematopoietic stem/progenitor cells using a defined 3D culture system

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