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Mesenchymal Stem Cells

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iPSC-MSC in vivo Study Uncovers Novel Immunomodulatory Mechanism

Researchers studying the effects of iPSC-MSCs treatment in an in vivo mouse model discover a novel immunomodulatory mechanism involving caspase proteins

Adipose Tissue and Immunomodulation: It’s not what you do, it’s where you do it!

New research indicates that adipogenic differentiation of mesenchymal stem cells alters their immunomodulatory capabilities, with consequences for inflammatory disorders

MMP2: The Key to MSC-based Treatments of PD?

A new study demonstrates that a metalloproteinase secreted by mesenchymal stem cells can effectively degrade the -synuclein aggregates associated with Parkinson’s Disease

Effective Tooth Repair with Mobilized MSCs!

Researchers describe a small molecule-mediated strategy to mobilize tooth pulp stem cells and repair large tooth lesions

Combination of Common Pesticides Detrimental to Mesenchymal Stem Cells

Researchers discover that a combination of pesticides at low concentrations can detrimentally affect human mesenchymal stem cells

Two is better than one for MSC Treatment of Retinal Degeneration

Researchers discover that a combination MSC treatment inhibits retinal degeneration and vision loss in a mouse model

The hMSC Secretome: An Effective Cell-free Therapy for Parkinson’s Disease?

New research suggests that hMSC-secreted factors can successfully treat some of the symptoms of Parkinson’s Disease

Enhanced hMSC-based Therapies via Metabolic Rewiring?

New research suggests that changes to the metabolic profile of aggregated hMSCs enhance stem cell characteristics

Promoting Cardiac Regeneration with an Effective Cell-Free Strategy

An exosome-based cell-free combination strategy shows great potential for the treatment of heart conditions

Quiescence: A Simple and Effective Strategy to Enhance Stem Cell Survival?

Researchers have discovered that inducing quiescence in stem cells may be an effective means to enhance stem cell survival

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