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Mesenchymal Stem Cells

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Successful First in Man Trial for MSC-based Cartilage Repair

Researchers report on a successful cartilage repair trial using a simple strategy involving mesenchymal stem cell and patient-derived chondrocytes

Phase II for Allogeneic BM-MSC Treatment of Aplastic Anemia!

The results of a new trial suggest that allogeneic bone marrow-derived mesenchymal stem cells may represent an effective means to treat a bone marrow failure disorder

HIF-MSC Exosomes: An Efficient and Effective Strategy to Promote Angiogenesis?

A new study indicates that exosomes derived from stem cells overexpressing the HIF-1α transcription factor can promote angiogenesis in vitro and in vivo

MSC-based Neo Islets: The Future of Long Term Diabetes Control?

A new study describes how Neo Islets composed of mesenchymal stem cells and allogeneic islet cells may be the future of type I diabetes treatment

iPSC-MSC in vivo Study Uncovers Novel Immunomodulatory Mechanism

Researchers studying the effects of iPSC-MSCs treatment in an in vivo mouse model discover a novel immunomodulatory mechanism involving caspase proteins

Adipose Tissue and Immunomodulation: It’s not what you do, it’s where you do it!

New research indicates that adipogenic differentiation of mesenchymal stem cells alters their immunomodulatory capabilities, with consequences for inflammatory disorders

MMP2: The Key to MSC-based Treatments of PD?

A new study demonstrates that a metalloproteinase secreted by mesenchymal stem cells can effectively degrade the -synuclein aggregates associated with Parkinson’s Disease

Effective Tooth Repair with Mobilized MSCs!

Researchers describe a small molecule-mediated strategy to mobilize tooth pulp stem cells and repair large tooth lesions

Combination of Common Pesticides Detrimental to Mesenchymal Stem Cells

Researchers discover that a combination of pesticides at low concentrations can detrimentally affect human mesenchymal stem cells

Two is better than one for MSC Treatment of Retinal Degeneration

Researchers discover that a combination MSC treatment inhibits retinal degeneration and vision loss in a mouse model

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