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Mesenchymal Stem Cells

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Organ-Specific “Tissue Papers” Created from Extracellular Matrix Ink

Researchers have developed a new means to utilize decellularized extracellular matrix in regenerative strategies including the maintenance of ovarian tissue 

Enhanced Bone Fracture Healing with Engineered Mesenchymal Stem Cells

The overexpression of basic fibroblast growth factor boosts bone fracture healing capacity of mesenchymal stem cells via the secretion of paracrine-acting factors

CAMKK1 Overexpression: A New and Effective Strategy to Improve Cardiac Repair?

A new study suggests that CAMKK1 overexpression in mesenchymal stem cells can potentiate cardiac repair via the modulation of secreted paracrine acting factors

MSC-treatment of Parkinson’s Disease: A New Mechanism Uncovered!

A new study suggests that protection against axonal defects represents a new mechanism involved in MSC-treatment of early stage Parkinson’s Disease

Successful First in Man Trial for MSC-based Cartilage Repair

Researchers report on a successful cartilage repair trial using a simple strategy involving mesenchymal stem cell and patient-derived chondrocytes

Phase II for Allogeneic BM-MSC Treatment of Aplastic Anemia!

The results of a new trial suggest that allogeneic bone marrow-derived mesenchymal stem cells may represent an effective means to treat a bone marrow failure disorder

HIF-MSC Exosomes: An Efficient and Effective Strategy to Promote Angiogenesis?

A new study indicates that exosomes derived from stem cells overexpressing the HIF-1α transcription factor can promote angiogenesis in vitro and in vivo

MSC-based Neo Islets: The Future of Long Term Diabetes Control?

A new study describes how Neo Islets composed of mesenchymal stem cells and allogeneic islet cells may be the future of type I diabetes treatment

iPSC-MSC in vivo Study Uncovers Novel Immunomodulatory Mechanism

Researchers studying the effects of iPSC-MSCs treatment in an in vivo mouse model discover a novel immunomodulatory mechanism involving caspase proteins

Adipose Tissue and Immunomodulation: It’s not what you do, it’s where you do it!

New research indicates that adipogenic differentiation of mesenchymal stem cells alters their immunomodulatory capabilities, with consequences for inflammatory disorders

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