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Neural Stem Cells

Single-Cell Probing of Neural Progenitors

Clonal analysis in histology and single-cell transcriptomics have shed new light on our understanding of forebrain germinal activity at pre‐ and post‐natal time points.

Herpes Simplex Virus Impairs Adult Neurogenesis

A new study from the labs of Roberto Piacentini and Claudio Grass

CD71 as a Negative Selection Marker for Neurons

A recent STEM CELLS study from the lab of Jan Pruszak (University of Freiburg, Freiburg, Germany) describes an exhaustive characterization of neural cell types by surface antigens, exploiting human pluripotent stem cell‐derived neural cell syste

Study Highlights the Role of Migratory Neural Progenitor Cells in Prostate Cancer Development

NPCs migrate through the blood to target primary tumors or metastatic tissues where the initiate neurogenesis and support the development of prostate cancer

Neural Stem Cells from Neuroepithelial Stem Cells

A recent study from the labs of Philipp Koch (University of Heidelberg/Medical Faculty Mannheim) and

Neural Stem Cell Interactions with Drugs

Neurodegenerative disease treatment may include the development of both stem cell- and pharmacology-based approaches; however, we know little about how neural stem cells, for example, and drugs interact.

Neonatal Astrocytes Promote NSC Proliferation Via TNC

Recent studies demonstrating that molecules secreted from astrocytes play crucial roles in neural stem cells (NSCs) fate determination, researchers sought to understand this process towards creating new strategies to treat traumatic brain injury (TBI).

Autophagy Induction by Neural Stem Cell-derived Extracellular Vesicles Aids Recovery from Spinal Cord Injury

Extracellular vesicle-based approach afforded a reduction in neuronal apoptosis and neuroinflammation and an increase in functional recovery at early stages thanks to the induction of autophagy

NSC Treatment Feasible for Motor Stroke

A recent STEM CELLS Translational Medicine article reports the findings of a single‐site, phase I study of the transplantation of human neural stem cells (NSCs) for the treatment of hemiparesis due to chronic motor stroke. Researchers from the labs of Karl K.

Senescent NPCs in Progressive Multiple Sclerosis: A New Therapeutic Target?

New research establishes senescent NPCs as a contributor to and potentially reversible factor in progressive MS while also suggesting MS as an aging-related disease

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