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Neural Stem Cells

Senescent NPCs in Progressive Multiple Sclerosis: A New Therapeutic Target?

New research establishes senescent NPCs as a contributor to and potentially reversible factor in progressive MS while also suggesting MS as an aging-related disease

Human Neural Stem Cell Therapy in Amyotrophic Lateral Sclerosis

Protecting the Fetus from Diabetes-associated Central Nervous System Damage with Melatonin

Researchers investigate the hypothesis that hyperglycemia may influence autophagy in neural stem cells and that melatonin may act as a protective agent

Labeling Technique Permits Tracking of Stem Cell Transplants in Amyotrophic Lateral Sclerosis Patients

Fluorine‐19 labeling for MRI‐based cell tracking does not affect the fundamental neuroprotective properties of human glial‐restricted progenitors

Uncovering the Routes Linking Stroke to Neural Stem Cell Proliferation and Differentiation

A new study investigates the signaling pathways linking stroke and neural stem cell function with a focus on blood‐brain barriers in brain stem cell niches

Subventricular Zone Neural Stem Cells Identified as Cell of Origin for Glioblastoma

Researchers employing cutting-edge techniques highlight stem cells from the subventricular zone of the brain as the cell of origin for an incurable brain tumor

Assessing NSC Transplantation as a Treatment Approach for Parkinson’s Disease in Aged Patients

A new study of NSC transplantation into the aged brain highlights a critical role for astrocyte and Wnt/β‐catenin signaling in nigrostriatal mDA neuron restoration

Boosting Hippocampal Neurogenesis to Treat Cognitive Dysfunction

A novel compound that increases neurogenesis in the hippocampus may represent a new means to treat hippocampus-associated cognitive dysfunction

Motor Cortex Targeting Improves Treatment of ALS by Engineered Human Neural Progenitor Cells

Researchers establish that transplantation of growth factor-secreting human NPCs can delay paralysis and extend lifespan in a rat model of ALS

Engineered Neuroepithelial Stem Cells: A Safe Means to treat Central Nervous System Disorders?

German researchers describe a new stem-cell based strategy to deliver adenosine to the brain as a treatment for central nervous system disorders

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