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MSC-Derived Extracellular Vesicle Therapy

A new review article from the laboratory of David S. Allan (University of Ottawa, Ontario, Canada) highlights the progress made in mesenchymal stem cell (MSC)‐derived small extracellular vesicle (EV)‐based therapeutics. The team accomplish this feat by summarizing information regarding the starting material for MSC expansion, EV production, and isolation methods, studies from preclinical models that have established a foundation of knowledge to support translation into the patient setting, and potential barriers to overcome on the path to clinical application. For all the details, see STEM CELLS Translational Medicine now!