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Induced pluripotent stem cells could serve as cancer vaccine

Induced pluripotent stem cells, or iPSCs, are a keystone of regenerative medicine. Outside the body, they can be coaxed to become many different types of cells and tissues that can help repair damage due to trauma or disease. Now, a study in mice from the Stanford University School of Medicine suggests another use for iPSCs: training the immune system to attack or even prevent tumors.

The results suggest it may one day be possible to vaccinate an individual with his or her own iPSCs to protect against the development of many types of cancer.

Progress reported in search of a cure for sickle cell anemia

Scientists have successfully used gene editing to repair 20 to 40 percent of stem and progenitor cells taken from the peripheral blood of patients with sickle cell disease, according to Rice University bioengineer Gang Bao, Ph.D.

Dr. Bao, in collaboration with Baylor College of Medicine, Texas Children’s Hospital and Stanford University, is working to find a cure for the hereditary disease. A single DNA mutation causes the body to make sticky, crescent-shaped red blood cells that contain abnormal hemoglobin and can block blood flow in limbs and organs.

What’s the Stem Cells Buzz this Week? - Repolarizing Macrophages, Understanding CD133, Corneal transplantation, and Short Telomeres in CPCs!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Researchers Discover how Notch Duo Coordinate Muscle Stem Cell Regulation

A new STEM CELLS study describes how two members of the regeneration-associated Notch signaling pathway combine to coordinate muscle stem cell regulation

Stem Cells: License to be Pluripotent!

New research from the University of North Carolina establishes a link between rapid origin licensing and the maintenance of stem cell pluripotency

What’s the Stem Cells Buzz this Week? – Enhancing MSC Osteogenesis, Trialing Cord Blood for Autism, The Role of LSCs in CML Treatment, and Promoting HSPC Survival by NFIX!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Stem cell discovery could advance cattle production and help study human disease

For more than 35 years, scientists have tried to isolate embryonic stem cells in cows without much success. Under the right conditions, embryonic stem cells can grow indefinitely and make any other cell type or tissue, which has huge implications for creating genetically superior cows.

In a study just published in Proceedings of the National Academy of Sciences, scientists at the University of California, Davis, were able to develop a new culture system that allows them to efficiently derive stem cells on almost every single attempt.

Small molecule could make a big difference for arthritis patients

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? A research team in the University of Southern California’s Keck School of Medicine has reason to be optimistic.

Scientists create functioning kidney tissue

Scientists have successfully produced human kidney tissue within a living organism that is able to produce urine, a first for medical science. The study, led by Sue Kimber, Ph.D., and Adrian Woolf, M.D., from the University of Manchester, signifies a significant milestone in the development of treatment for kidney disease.

Researchers report first lung stem cell transplantation clinical trial

A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. For the first time, researchers have regenerated patients' damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial.

For patients suffering from chronic pulmonary diseases, lung stem cell transplantation could be their best, if not last hope.


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