DURHAM, NC - Each year in the United States more than 300,000 people are hospitalized for hip fractures. Almost half never recover well enough to live an independent lifestyle and, even worse, the one-year mortality rate is high, ranging from 12 percent to 37 percent.
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Press Releases from AlphaMed Press
Embargo Policy: Articles for STEM CELLS and STEM CELLS Translational Medicine are embargoed for release until 9 a.m. Eastern U.S. time on the day the article is posted online. This policy applies to members of the media, authors, institutions' public information officers, and the public. Authors may not discuss their work with the media until 1 week before the mailing date or 1 week before online posting of the article, whichever is earlier, and must ensure that the media representatives agree to abide by the embargo policy. STEM CELLS Translational Medicine may refuse to publish a manuscript, despite acceptance for publication, if it has been prematurely released to the press.
A new review is the first to directly examine the role of various stem cells in the healing of wounded cornea, the outermost part of the eye. In contrast with most other reviews, it covers all major corneal cell types in a comprehensive way, showing similarities and differences in the healing process and the usage of stem cells for therapy.
Corneal wound healing is a complex process that occurs in response to various eye injuries and surgery. Delayed, incomplete, or excessive healing is a significant clinical concern. The review presents evidence on the participation of stem cells in corneal wound healing and highlights how stem cell transplantation may be used to fine tune wound healing and provide benefits for patients.
DURHAM, NC - Studies indicate that replacing damaged brain cells with those derived from human embryonic stem cells might lead to an effective treatment for Parkinson’s disease. But what has not been determined is the optimal stage during differentiation of the stem cells that the transplantation should take place to gain the best results.
DURHAM, NC - A study recently published in STEM CELLS Translational Medicine shows smooth muscle and vascular endothelial cells induced from pluripotent stem cells perform similarly to their naturally evolving counterparts under conditions that mimic hardening of the arteries and other blood vessel diseases. The finding opens the door to modeling rare vascular diseases necessary for research, as well as assists in screening new drugs and developing personalized cell-based therapies.
DURHAM, NC - A new study demonstrates how an infusion of stem cells can assist in treating severe cases of aplastic anemia (AA) that do not respond to immunosuppressive therapy (IST) alone. The study, which appears in STEM CELLS Translational Medicine (SCTM), offers hope for patients with this rare disease, which occurs when the bone marrow does not produce enough blood cells to meet the body’s needs.
DURHAM, NC - AlphaMed Press and the Cord Blood Association (CBA) are pleased to announce that STEM CELLS Translational Medicine (SCTM) is now the association’s official journal. With this partnership, SCTM will launch a new journal section dedicated to cord blood research.
“We are delighted to initiate this partnership with the Cord Blood Association,” said Anthony Atala, M.D., Editor-in-Chief of STEM CELLS Translational Medicine and Director of the Wake Forest Institute for Regenerative Medicine. “With this new journal section, SCTM further expands the scope of new research reports for our readers – with the potential to accelerate progress in regenerative medicine.”
DURHAM, NC - Currently symptomatic therapies for Parkinson’s Disease (PD) produce unwanted side effects and diminished effectiveness over time. A recent study published in STEM CELLS suggests that human neural stem cell (hNSC) transplantation could help to treat PD by stimulating subventricular zone (SVZ) stem cells to produce more neural cells.
Strategies involving transplantation of these cells into the affected brain regions hold great promise; however, the exact mechanisms behind hNSCs’ success are not fully understood.
Neural stem cells are self-renewing and can differentiate into any type of neural cell, such as neurons and glial cells. With their ability to rescue dysfunctional neural pathways, NSCs are an ideal source for grafting and the development of novel therapies.
DURHAM, NC – A new study published this month in STEM CELLS Translational Medicine indicates that treating heart patients with mesenchymal stem cells (MSCs) does not increase their risk of irregular heart beat (arrhythmia). In fact, the MSCs had the opposite effect and showed promise of improving the condition.
“This could be an important breakthrough for many heart patients, as proarrhythmia – which is a new or more frequent occurrence of pre-existing arrhythmia – unfortunately can be a side effect of some of the drugs we’re using to treat these patients,” said the study’s lead author, Raul Mitrani, M.D., of the University of Miami School of Medicine’s Division of Cardiology (Miami, Florida).
DURHAM, NC - An infusion of a healthy donor’s unmodified stem cells might one day be used to prevent a type of osteoporosis caused by glucocorticoid therapy, according to a study published this month in STEM CELLS Translational Medicine. Osteoporosis is among the most significant side effects of glucocorticoid therapy, which is used for the management of inflammatory and auto-immune diseases.
DURHAM, NC - Researchers for the first time have shown how engineered stem cells can be used to deliver antibodies superior to those currently available for protecting against infectious diseases and biological warfare. The study appears in the August issue of STEM CELLS Translational Medicine.