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Brief reviews of recently published articles, organized by stem cell type.

October 18, 2010 | Pluripotent Stem Cells

The first official clinical trial using stem cells to treat patients with spinal injury is now underway (also see ‘US give Geron Go-ahead for ESC Trial for Spinal Cord Injury’). The first patient to receive the trial treatment was enrolled on Monday at Shepherd Center in Atlanta, Georgia. Another 9 patients who have recently suffered spinal cord injuries will be enrolled from 6 other potential...

October 12, 2010 | Pluripotent Stem Cells

Research published in the 30th September edition of Cell Stem Cell reports that human induced pluripotent stem cells (hiPSCs) can be rapidly and efficiently derived with messenger RNA (mRNA). This research, from the laboratory of Derrick Rossi shows that daily transfection of differentiated human cells with modified synthetic mRNAs encoding the four canonical Yamanaka factors KLF4, c-MYC,...

September 20, 2010 | Pluripotent Stem Cells

With each month’s Featured Lab Series, the Stem Cells Portal extend an invitation to one of the Featured Lab members to contribute a short review of a paper of their interest for feature on the Stem Cells Portal. This month, Minh Hong from the Kaufman Laboratory has contributed an article which focuses on a key paper published recently in PNAS that addresses the further evolution of...

September 17, 2010 | Pluripotent Stem Cells

By Stuart P. Atkinson

DNA looping to allow proximity of enhancers and promoter sequences has been suggested as a means to regulate gene expression, but the mechanisms by which this occurs and the factors involved are still to be fully understood. However an advance online publication from Nature uncovers a mechanism by which DNA-looping-mediated regulation of gene expression...

September 9, 2010 | Pluripotent Stem Cells

Know which way to miRoam: Red means ‘GO’, Green ‘STOP’!

By Carla B. Mellough

Induced pluripotent stem cells (iPSC) are shown to have many of the characteristics of human embryonic stem cells (hESC) including prolonged proliferative capacity and differentiation across all germ layers. The therapeutic potential of human iPSC (hiPSC),...

August 30, 2010 |

By Maria H. Ledran

In the mid 1930’s the unlikely collaborators aviator Charles Lindberg and maverick surgeon Alexis Carrel, were the first to sustain whole organs outside the body for extended periods using their newly invented glass perfusion pumps. Arguably the unique methods set out by the pair including the anastomy (suturing) of even the most miniscule blood vessels and...

August 26, 2010 | Pluripotent Stem Cells

STEM CELLS’ Position Statement on hESC Research

Durham, North Carolina, August 27, 2010 — The Journal STEM CELLS® has published many important and exciting achievements in the field of stem cells during its twenty-eight year history. Through scientific discovery, the Journal reports on both adult and human embryonic stem cells (hESCs). The...

August 26, 2010 |

Durham, North Carolina, August 27, 2010 — The Journal STEM CELLS® has published many important and exciting achievements in the field of stem cells during its twenty-eight year history. Through scientific discovery, the Journal reports on both adult and human embryonic stem cells (hESCs). The Journal believes that the scientific community benefits from research on...

August 26, 2010 |

Durham, North Carolina, August 27, 2010 — The Journal STEM CELLS® has published many important and exciting achievements in the field of stem cells during its twenty-eight year history. Through scientific discovery, the Journal reports on both adult and human embryonic stem cells (hESCs). The Journal believes that the scientific community benefits from research on...

August 13, 2010 | Pluripotent Stem Cells

From Cell Stem Cell

Research published in the 6th August edition of Cell Stem Cell suggests that human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) may be more similar than previously thought. This research, from the laboratory of...

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