Systematic evaluation of methods to differentiate dopaminergic neurons from hPSCs identifies measures to improve comparisons and clinical translation
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Brief reviews of recently published articles, organized by stem cell type.
April 15, 2019 | ESCs/iPSCs
April 15, 2019 | Neural Stem Cells
Researchers investigate the hypothesis that hyperglycemia may influence autophagy in neural stem cells and that melatonin may act as a protective agent
April 15, 2019 | Aging
Activation of retrotransposons contributes to inflammaging, although the L1 reverse transcriptase represents a target for age-associated disorder treatment
April 8, 2019 | Neural Stem Cells
Fluorine‐19 labeling for MRI‐based cell tracking does not affect the fundamental neuroprotective properties of human glial‐restricted progenitors
April 8, 2019 | Cancer Stem Cells
Characteristics of the tumor microenvironment can inhibit CHD7 expression in glioblastoma tumor-initiating cells and prompt a pro-angiogenic response
April 8, 2019 | Direct Reprogramming
Researchers refine a chemical cocktail to four small molecule drugs and define the signaling pathways vital for astrocytes-neuron conversion
April 1, 2019 | Limbal Stem Cells
Trial Provides Impetus for Autologous Limbal Stem Cell Transplantation in Vision Threatening Disease
A phase I/II trial examines allogeneic corneal epithelial stem cells cultured on amniotic membrane at GMP standard for the treatment of bilateral LSCD
April 1, 2019 | ESCs/iPSCs
Immature hPSC-derived pancreatic β cell clustering in vitro promotes the generation of mature β cells that resemble their endogenous counterparts
March 18, 2019 | Cord Blood Stem Cells
A new study reports the results of a trial comparing intra‐articular injection of umbilical cord MSCs for the treatment of human knee osteoarthritis
March 18, 2019 | ESCs/iPSCs
New research highlights the influence of a GPCR effector on the maintenance of hESC pluripotency and the successful reprogramming of fibroblasts to hiPSCs
