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Clinical Trials: Cord Blood
Interventions: Procedure: Allogeneic Hematopoietic Stem Cell Transplantation; Drug: Busulfan; Drug: Cyclophosphamide; Drug: Fludarabine Phosphate; Other: Laboratory Biomarker Analysis; Drug: Melphalan; Drug: Methotrexate; Drug: Momelotinib; Drug: Mycophenolate Mofetil; Drug: Pacritinib; Drug: Ruxolitinib; Drug: Tacrolimus; Radiation: Total-Body Irradiation; Procedure: Umbilical Cord Blood Transplantation
Sponsors: Fred Hutchinson Cancer Research Center; National Cancer Institute (NCI); National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2017
Interventions: Drug: Cyclophosphamide; Drug: Thiotepa; Drug: Fludarabine; Drug: Melphalan; Drug: Mesna; Biological: G-CSF; Drug: Mycophenolate mofetil; Drug: Tacrolimus; Drug: Methylprednisolone; Radiation: Total lymphoid irradiation; Biological: Lymphocyte infusions; Device: CliniMACS
Sponsor: St. Jude Children's Research Hospital
Recruiting - verified August 2016
Interventions: Drug: cyclophosphamide; Drug: fludarabine phosphate; Radiation: total-body irradiation; Drug: cyclosporine; Drug: mycophenolate mofetil; Procedure: umbilical cord blood transplantation; Procedure: mesenchymal stem cell transplantation
Sponsors: Case Comprehensive Cancer Center; National Cancer Institute (NCI)
Interventions: Drug: Reduced Toxicity Ablative Regimen; Drug: Reduced Intensity Preparative Regimen; Drug: Myeloablative Preparative Regimen
Sponsor: Masonic Cancer Center, University of Minnesota
Interventions: Biological: unrelated BM with T cell depletion; Biological: unrelated cord blood; Biological: haplo BM with T cell depletion; Device: unrelated PBSC with T cell depletion
Sponsor: Neena Kapoor, M.D.
Interventions: Drug: Fludarabine; Procedure: Hematopoietic Stem Cell Transplant (HSCT)
Sponsor: Case Comprehensive Cancer Center
Recruiting - verified July 2017
Interventions: Biological: human umbilical cord blood derived mesenchymal stem cells; Other: Normal saline 2mL
Sponsor: Medipost Co Ltd.
Recruiting - verified April 2017
Intervention: Genetic: Autologous Stem Cells
Sponsors: James Baumgartner, MD; CBR Systems, Inc.
Intervention: Device: Stem Cell Educator
Sponsors: Tianhe Stem Cell Biotechnologies Inc.; Second Xiangya Hospital of Central South University
Intervention: Biological: Stem cells
Sponsor: Kang Stem Biotech Co., Ltd.
Recruiting - verified September 2016