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The Best Papers from our 2015 Young Investigators

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The STEM CELLS Young Investigator Award honors a young scientist who is principal author of a significant research paper published in STEM CELLS. The 10th annual award went to Kamil R. Kranc, M.D., Ph.D. Here, we feature Professor Kranc’s paper, chosen by a panel of judges composed of our Senior Editors. Also included below are the finalists for the 2015 award. The STEM CELLS Editors support the efforts of these emerging researchers and encourage the development of these young investigators who are making significant impacts in this field, thus fostering the future of their clinical applications.

Find out more about the winner of the 2015 STEM CELLS Young Investigator Award.


Acute Loss of Cited2 Impairs Nanog Expression and Decreases Self-Renewal of Mouse Embryonic Stem Cells
Kamil R. Kranc, Daniel V. Oliveira, Alejandro Armesilla-Diaz, Ivette Pacheco-Leyva, Ana Catarina Matias, Ana Luisa Escapa, Chithra Subramani, Helen Wheadon, Marlene Trindade, Jennifer Nichols, Keisuke Kaji, Tariq Enver, and José Bragança

Somatic Cells with a Heavy Mitochondrial DNA Mutational Load Render Induced Pluripotent Stem Cells with Distinct Differentiation Defects
Martin Wahlestedt, Adam Ameur, Roksana Moraghebi, Gudmundur L. Norddahl, Gerd Sten, Niels-Bjarne Woods and David Bryder

Recruited Brain Tumor-Derived Mesenchymal Stem Cells Contribute to Brain Tumor Progression
Jinan Behnan, Pauline Isakson, Mrinal Joel, Corrado Cilio, Iver A. Langmoen, Einar O. Vik-Mo, and Wiaam Badn

Mesenchymal Stem/Stromal Cells Inhibit the NLRP3 Inflammasome by Decreasing Mitochondrial Reactive Oxygen Species
Joo Youn Oh, Jung Hwa Ko, Hyun Ju Lee, Ji Min Yu, Hosoon Choi, Mee Kum Kim, Won Ryang Wee, and Darwin J. Prockop

The Orphan Nuclear Receptor NR4A1 Specifies a Distinct Subpopulation of Quiescent Myeloid-Biased Long-Term HSCs
Ruben H. Land, Anna K. Rayne, Ashley N. Vanderbeck, Trevor S. Barlowe, Shwetha Manjunath, Matthew Gross, Sophie Eiger, Peter S. Klein, Nicole R. Cunningham, Jian Huang, Stephen G. Emerson, and Jennifer A. Punt

Mesenchymal Stem Cells Reduce Intervertebral Disc Fibrosis and Facilitate Repair
Victor Y.L. Leung, Darwesh M.K. Aladin, Fengjuan Lv, Vivian Tam, Yi Sun, Roy Y.C. Lau, Siu-Chun Hung, Alfonso H.W. Ngan, Bin Tang, Chwee Teck Lim, Ed X. Wu, Keith D.K. Luk, William W. Lu, Koichi Masuda, Danny Chan, and Kenneth M.C. Cheung

Click here to read the interview with the STEM CELLS 2015 Young Investigator Award winner.